In this session we will dive deep into the advanced clientspecific apis for building addins in excel, word, and powerpoint. Name of the medicinal product oncaspar solution for injection 2. Work with the most accurate pdf to powerpoint converter. To minimize the risk of complications when initiating iv therapy through. Interfere with blood clotting by blocking the activity of thrombin, e. The ndc code 0944381001 is assigned to oncaspar also known as. Follow these steps to use adobe acrobat to combine or merge word, excel, powerpoint, audio, or video files, web pages, or existing pdfs. Pegaspargase, a human prescription drug labeled by baxalta us inc. It is not known if oncaspar passes into breast milk. Tech support scams are an industrywide issue where scammers trick you into paying for unnecessary technical support services.
Pegaspargase, sold under the trade name oncaspar, is a medication used in the treatment of acute lymphoblastic leukemia all. Medlineplus information on pegaspargase a lay language summary of important information about this drug that may include the following. Withdraw volume of reconstituted elspar containing calculated dose into sterile syringe. Do not use if the oxygen indicator has turned blue or purple before opening the package see how suppliedstorage and handling 16. Combine or merge files into a single pdf, adobe acrobat dc. When utilized as a component of induction therapy for all, 1 dose of oncaspar achieved similar levels of asparagine depletion as 9 doses of native lasparaginase. Common side effects include allergic reactions, blood clotting problems, high blood sugar, liver problems, pancreas inflammation, and blood clots in the brain. P030 desensitization protocol for pegaspargase anaphylaxis. Shires shpg marketing authorization application for a new dried formulation of its leukemia drug, oncaspar receives approval from the european commission.
For iv administration, reconstitute elspar by adding 5 ml sterile water for injection or sodium chloride injection to the 10,000 unit vial. Advanced office addin development with excel, word. Worlds best powerpoint templates crystalgraphics offers more powerpoint templates than anyone else in the world, with over 4 million to choose from. Open powerpoint and display the slide where you want to insert the pdf text. Turn your pdf presentations to editable powerpoint ppt and pptx slideshows. Antigenspecific immune responses to protein drugs can hinder efficacy and compromise safety because of drug neutralization and secondary clinical complications. Before we begin, you should be aware of the two ways you can do this.
Fulltext pdf costeffectiveness of drugeluting stents in elderly patients with coronary artery disease. Read more about the prescription drug pegaspargase injection. Occasionally, the package insert component of product labeling for drugs that have received fda approval for commercial use is prefaced by prominent precautionary and warning summaries circumscribed by a rectangular border, commonly referred to as black box warnings, or, simply, boxed warnings. For further product information and current package insert, please visit. Side effects of oncaspar pegaspargase, warnings, uses. When using an intravenous infusion pump, administer integrilin undiluted directly from the 100ml vial. The fda previously approved oncaspar only for patients with all who were unable to receive the cancer drug lasparaginase because of an allergy. Pegaspargase oncaspar is a modified form of native e coli asparaginase in which the enzyme is covalently linked to polyethylene glycol.
If you go with this option, you probably want to keep the pdf file as a supporting document for your powerpoint presentation. Withdraw the bolus doses of integrilinfrom the 10ml vial into a syringe. Detecting and treating asparaginaserelated toxicities in. Inhibit the production of certain clotting factors in the liver, e. Baxalta granted eu marketing authorization for oncaspar pegaspargase as a component of combination therapy in acute lymphoblastic leukaemia all all is a rare blood cancer that affects. Governorsgeneral from four countries brothersinlaw and their wives. Free powerpoint templates of the famous 4ps marketing mix and extended models. Oncaspar can be given by intramuscular injection or intravenous infusion. Definition from the nci drug dictionary detailed scientific definition and other names for this drug. If your pdf is in a presentation format, the conversion should be no problem.
If the identification number is missing, or different from the stated number above, the strip should not be used. During pregnancy, oncaspar should be used only when prescribed. A prospective study on drug monitoring of pegasparaginase and erwinia asparaginase and asparaginase antibodies in pediatric acute lymphoblastic leukemia. This study included three cohorts of pediatric leukemia patients treated upfront with pegaspargase. Theyll give your presentations a professional, memorable appearance the kind of sophisticated look that. Save money on your ifosfamide injection prescription by switching to tevas fdaapproved generic version. How to insert a pdf into powerpoint online tech tips.
The reconstituted solution contains 5,000 international units iuml. Ppt drug education powerpoint presentation free to. Modified smile msmile is active in the treatment of extranodal natural. Oncaspar, 48 patients 81% received all 3 planned doses of oncaspar, 6 10% received 2 doses, 4 7% received 1 dose, and 1 patient 2% did not receive the assigned treatment. Specific id number 53 verify the specific identification number before use. Parenteral drug products should be inspected visually for particulate matter and discoloration prior to. The proposed package insert document is usually created in microsoft word and submitted as part of the final labeling folder. It is ideal for presenting data contained within other. It should be administered no more frequently than every 14 days. The use of oncaspar in place of lasparaginase reduces the number of drug injections required, from 21 injections of lasparaginase to three injections with oncaspar over the 20week course of treatment.
Drug preparation and administration hematologyoncology. For purpose of this study, the drug was given as a single intravenous dose. Shires new formulation of oncaspar gets approval in europe. Changes may be necessary because of hypersensitivity reactions or availability. Search the drug product database dpd to find drugs authorized for sale by health canada.
See full prescribing information for 3,750 international units5 ml solution in a singleuse vial. Pegaspargase in the treatment of acute lymphoblastic leukemia. One main difference that you may experiment while working with powerpoint web apps is the concept of themes and variants. If youre creating a microsoft powerpoint presentation, you can insert a pdf document by following these steps. The quality of the pdf file is reduced with this method, but you can open the full pdf file by doubleclicking the image when viewing or editing in normal view. Pharmacodynamics and safety of intravenous pegaspargase during.
Insert pdf file content into a powerpoint presentation. The recommended dose of oncaspar is 2,500 ium 2 intramuscularly im or intravenously iv. The pdf file should be the first option within the insert dialog window. Due to the risk of hyperbilirubinaemia, it is recommended to monitor bilirubin levels at baseline and prior to each dose. Do not mix reagents from different lots within a given test run. Immediately following the bolus dose administration, initiate a continuous infusion of integrilin. You can help protect yourself from scammers by verifying that the contact is a microsoft agent or microsoft employee and that the phone number is an official microsoft global customer service number. This medication is given by injection into a vein or a muscle by a health care professional. To form the plurals of hyphenated nouns, add s only to the first word.
We report a tolerance induction strategy to prevent antigenspecific humoral immune responses to therapeutic proteins. Baxter to buy oncaspar product portfolio from sigmatau. Inserting a pdf as an image is a quick way to present flat data in a noninteractive fashion. Powerpoint web apps is the online free version of powerpoint that has the new metro interface and features that you will find in the office 20 version. Insert pdf file content into a powerpoint presentation powerpoint. Sip3d package concepts multiple component packageinpackage packageonpackage powerpoint presentation. Modified smile msmile is active in the treatment of extranodal.
Product information nordette tablets name of the medicine levonorgestrel and ethinyloestradiol chemically, ethinyloestradiol is 19nor17 pregna1,3,510trien20yne3,17diol and has. Pegaspargase pegasparjace destroys leukemia cancer cells in the first growth g 1 phase of cell life. Lyophilized oncaspar builds on more than a decade of data and research with liquid oncaspar, and with no change in dosing regimen, it offers a threetimes longer shelf life, said howard b. Primary structure is the order or sequence of amino acid residues peptides are always written and named with the amino terminus on the left and the carboxy terminus on the right strong acid required to hydrolyse peptide bonds cysteine residues create disulfide bridges between chains this does not reveal primary structure dr. A pdf document is filled with all kinds of content, including text or images, that you might want to import elsewhere.
Using a pipette or psipette, pick up 14 colonies of identical morphology from the agar plate, either by suction or by successive touches. The products dosage form is injection, solution, and is administered via intramuscular. Not known whether pegaspargase is distributed into milk. The acquisition further accelerates the innovation capabilities and the commercial presence of baxter bioscience in growing oncology markets for rare and orphan diseases. Show possession by adding s at the end of the word. Combine files into a single pdf, insert a pdf into another pdf, insert a clipboard selection into a pdf, or place insert a pdf as a link in another file. Once the overwrap package is opened, use within 24 hours see storage and handling 16.
The marketing mix model, or marketing strategy also known as the 4 ps is widely used by marketers as a tool. This will bring up header and footer dialog, enable date and time option, and beneath it choose a. Oncaspar may interact with vincristine, prednisone, or methotrexate. Dosage is based on your body size and response to treatment. Direct costs hospitalization, drug administration, allergic reactions management were derived from gazzetta ufficiale. Click the image and it will be inserted into the slide. The package insert is also submitted in pdf and spl format. Oncaspar can be administered through intramuscular im injection or intravenous iv infusion. Tell your doctor all medications and supplements you use. Types of anticoagulants inhibitors of clotting factor synthesis. Often it is used together with anthracycline, vincristine, and prednisone. Generic drug manufacturers must update their pm to ensure it aligns with the canadian reference product. The governorgenerals car my brotherinlaws boat but. To bring you great quality, smallpdf has partnered with solid documents that offers the best conversion out there.
Fulltext pdf desensitization to protein kinase inhibitors. Engineered binding to erythrocytes induces immunological. How to insert date time in powerpoint 2010 presentation. Baxalta granted eu marketing authorization for oncaspar.
In this case, youll insert the entire pdf into the presentation as an object on a powerpoint slide, which you can open and view during presentation by selecting the pdf object. Each extended release tablet filmcoated tablet contains verapamil hydrochloride usp 240mg. Extract media files from a powerpoint presentation by ryan johnson, itech if you ever find that you need to use the images, video, or audio clips from a powerpoint presentation, but you dont have access to the original files, theres a trick you can use to extract all the media from the powerpoint file. Consumer information about the medication pegaspargase injection oncaspar, includes side effects, drug interactions, recommended dosages, and storage information. For smaller volumes of oncaspar, the preferred route of administration is intramuscular. Convert pdf to powerpoint convert your pdfs to powerpoint. Insert pdf content into your presentation either as a picture that shows on your slide, or as a document that you can open during your slide show. When oncaspar is given by intramuscular injection the volume injected at one site should not exceed 2 ml in children and adolescents and 3 ml in adults. Pegaspargase is also being studied in the treatment of other types of cancer. This should be taken into account when considering the use of oncaspar in these patient populations.
Pegaspargase injection oncaspar side effects, medical. The diagrams consist of colored circular shapes for each p central idea being the marketing mix name. Rules for compound nouns hyphenated nouns add to the confusion. Study 2 is an ongoing, multifactorial design study in which all patients received oncaspar as a component of various. It is given by injection shot into the muscle or as an infusion in the hospital or clinic. Although prior fda labeling submission requirements have been in the ms word and pdf formats, the fda now requires the package insert portion of.1202 1386 367 1335 1406 116 673 617 1402 898 174 799 538 1130 235 766 807 1010 507 878 754 649 766 1081 1208 1086 245 860 673 383 729 244 1307 474 1215 265 1070